Insulin glargine

Chemical formula: C₂₆₇H₄₀₄N₇₂O₇₈S₆  Molecular mass: 6,060.825 g/mol 

Active ingredient description

Insulin glargine is a human insulin analogue designed to have a low solubility at neutral pH. After injection, the acidic solution is neutralised leading to formation of a precipitate from which small amounts of insulin glargine are continuously released.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A10AE04 Insulin glargine A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10A Insulins and analogues → A10AE Insulins and analogues for injection, long-acting
Discover more medicines within A10AE04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
TOUJEO Solution for injection European Medicines Agency (EU) MPI, EU: SmPC
BASAGLAR Solution for injection Kwikpen / Tempo pen FDA, National Drug Code (US) MPI, US: SPL/PLR

External identifiers

CAS Substance: 160337-95-1
DrugBank Drug: DB00047
KEGG Drug: D03250
RxNorm Ingredient: 274783
SNOMED-CT Concept: 411529005
Insulin glargine (substance)
UNII Identifier: 2ZM8CX04RZ
INSULIN GLARGINE

Medicines

Insulin glargine is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Italy (IT)

Japan (JP)

Lithuania (LT)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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