ATC Group: A10A Insulins and analogues

Anatomical Therapeutic Chemical Classification System

Hierarchical position in ATC classification

Level
Code
Title
1
Alimentary tract and metabolism
2
Drugs used in diabetes
3
A10A
Insulins and analogues

ATC group contents

Code
Title
Insulins and analogues for injection, fast-acting
Insulins and analogues for injection, intermediate-acting
Insulins and analogues for injection, intermediate-acting combined with fast-acting
Insulins and analogues for injection, long-acting
Insulins and analogues for inhalation

Active ingredients

Active Ingredient
Description

The blood glucose lowering effect of insulin is due to the facilitated uptake of glucose following binding of insulin to receptors on muscle and fat cells and to the simultaneous inhibition of glucose output from the liver.

The blood glucose lowering effect of insulin aspart is due to the facilitated uptake of glucose following binding of insulin to receptors on muscle and fat cells and to the simultaneous inhibition of glucose output from the liver. Insulin aspart produces a more rapid onset of action compared to soluble human insulin, together with a lower glucose concentration, as assessed within the first four hours after a meal. Insulin aspart has a shorter duration of action compared to soluble human insulin after subcutaneous injection.

Insulin degludec binds specifically to the human insulin receptor and results in the same pharmacological effects as human insulin. The blood glucose-lowering effect of insulin is due to the facilitated uptake of glucose following the binding of insulin to receptors on muscle and fat cells and to the simultaneous inhibition of glucose output from the liver.

Insulin detemir is a soluble, long-acting insulin analogue with a prolonged duration of effect used as a basal insulin.

Insulin glargine is a human insulin analogue designed to have a low solubility at neutral pH. After injection, the acidic solution is neutralised leading to formation of a precipitate from which small amounts of insulin glargine are continuously released.

Insulin glulisine is a recombinant human insulin analogue that is equipotent to regular human insulin. Insulin glulisine has a more rapid onset of action and a shorter duration of action than regular human insulin.

The primary activity of insulin lispro is the regulation of glucose metabolism.

Related product monographs

Title
Type
Country
Summary of product characteristics (SPC)
Summary of product characteristics (SPC)
Structured product labeling (SPL/PLR)
US
Summary of product characteristics (SPC)
Structured product labeling (SPL/PLR)
US
Summary of product characteristics (SPC)
UK
Summary of product characteristics (SPC)
UK
Summary of product characteristics (SPC)
Summary of product characteristics (SPC)
Summary of product characteristics (SPC)
Structured product labeling (SPL/PLR)
US
Summary of product characteristics (SPC)
Summary of product characteristics (SPC)