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ATC Group: A10A Insulins and analogues

Anatomical Therapeutic Chemical Classification System

Hierarchical Position

Level
Code
Title
1
A
Alimentary tract and metabolism
2
A10
Drugs used in diabetes
3
A10A
Insulins and analogues

Contents

Code
Title
A10AB
Insulins and analogues for injection, fast-acting
A10AC
Insulins and analogues for injection, intermediate-acting
A10AD
Insulins and analogues for injection, intermediate-acting combined with fast-acting
A10AE
Insulins and analogues for injection, long-acting
A10AF
Insulins and analogues for inhalation

Active Ingredients

Chemical substance
Description
Insulin (human)

The blood glucose lowering effect of insulin is due to the facilitated uptake of glucose following binding of insulin to receptors on muscle and fat cells and to the simultaneous inhibition of glucose output from the liver.

Insulin (pork)
Insulin aspart

The blood glucose lowering effect of insulin aspart is due to the facilitated uptake of glucose following binding of insulin to receptors on muscle and fat cells and to the simultaneous inhibition of glucose output from the liver. Insulin aspart produces a more rapid onset of action compared to soluble human insulin, together with a lower glucose concentration, as assessed within the first four hours after a meal. Insulin aspart has a shorter duration of action compared to soluble human insulin after subcutaneous injection.

Insulin degludec

Insulin degludec binds specifically to the human insulin receptor and results in the same pharmacological effects as human insulin. The blood glucose-lowering effect of insulin is due to the facilitated uptake of glucose following the binding of insulin to receptors on muscle and fat cells and to the simultaneous inhibition of glucose output from the liver.

Insulin detemir

Insulin detemir is a soluble, long-acting insulin analogue with a prolonged duration of effect used as a basal insulin.

Insulin glargine

Insulin glargine is a human insulin analogue designed to have a low solubility at neutral pH. After injection, the acidic solution is neutralised leading to formation of a precipitate from which small amounts of insulin glargine are continuously released.

Insulin glulisine

Insulin glulisine is a recombinant human insulin analogue that is equipotent to regular human insulin. Insulin glulisine has a more rapid onset of action and a shorter duration of action than regular human insulin.

Insulin lispro

The primary activity of insulin lispro is the regulation of glucose metabolism.

Monographs

Monograph
Type
Country
ACTRAPID Solution for injection
MPI, EU: SmPC
ADMELOG Solution for injection
MPI, US: SPL/PLR
US
APIDRA Solution for injection
MPI, EU: SmPC
BASAGLAR Solution for injection Kwikpen / Tempo pen
MPI, US: SPL/PLR
US
HUMALOG 100 units/ml Solution for injection in vial / Cartridge / KwikPen - Junior KwikPen
MPI, EU: SmPC
HUMALOG 200 units/ml Solution for injection KwikPen pre-filled pen
MPI, EU: SmPC
HUMALOG Mix25 100 units/ml Suspension for injection in vial / cartridge / KwikPen pre-filled pen
MPI, EU: SmPC
HUMALOG Mix50 100 units/ml Suspension for injection in cartridge / KwikPen pre-filled pen
MPI, EU: SmPC
HUMULIN I Suspension for injection in a vial
MPI, EU: SmPC
UK
LEVEMIR Solution for injection
MPI, EU: SmPC
LYUMJEV Solution for injection
MPI, EU: SmPC
NOVORAPID Solution for injection in vial / Cartridge / Pre-filled pen
MPI, EU: SmPC
TOUJEO Solution for injection
MPI, EU: SmPC
TRESIBA Solution for injection
MPI, EU: SmPC