Schizophrenia

Active Ingredient: Aripiprazole

Indication for Aripiprazole

Population group: only adults (18 years old or older)

Aripiprazole is indicated for the treatment of schizophrenia in adults.

For this indication, competent medicine agencies globally authorize below treatments:

10-30 mg/day once a day

Route of admnistration

Oral

Defined daily dose

10 - 30 mg

Dosage regimen

From 10 To 30 mg once every day

Loading dose

10 mg

Detailed description

The recommended starting dose for aripiprazole is 10 or 15 mg/day with a maintenance dose of 15 mg/day administered on a once-a-day schedule without regard to meals. Aripiprazole is effective in a dose range of 10 to 30 mg/day. Enhanced efficacy at doses higher than a daily dose of 15 mg has not been demonstrated although individual patients may benefit from a higher dose. The maximum daily dose should not exceed 30 mg.

Elderly

The safety and efficacy of aripiprazole in the treatment of schizophrenia in Bipolar I Disorder in patients aged 65 years and older has not been established. Owing to the greater sensitivity of this population, a lower starting dose should be considered when clinical factors warrant.

Active ingredient

Aripiprazole

It has been proposed that aripiprazole’s efficacy in schizophrenia and Bipolar I Disorder is mediated through a combination of partial agonism at dopamine D2 and serotonin 5-HT1A receptors and antagonism of serotonin 5-HT2A receptors.

Read more about Aripiprazole

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