Extragenital condylomata acuminata

Active Ingredient: Podophyllotoxin

Indication for Podophyllotoxin

Population group: only adults (18 years old or older)

For the topical treatment of condylomata acuminata affecting the penis or the external female genitalia.

For this indication, competent medicine agencies globally authorize below treatments:

2 spreads in 2 divided doses daily

Route of admnistration

Cutaneous

Defined daily dose

2 - 2 {spreads}

Dosage regimen

From 1 To 1 {spreads} 2 time(s) per day every day for 3 day(s)

Detailed description

The affected area should be thoroughly washed with soap and water, and dried prior to application.

Using a fingertip, the cream should be applied twice daily morning and evening (every 12 hours) for 3 consecutive days using only enough cream to just cover each wart. The cream should then be withheld for the next 4 consecutive days.

Application to the surrounding normal tissue should be avoided.

Residual warts should be treated with further courses of twice daily applications for three days at weekly intervals, if necessary for a total of 4 weeks of treatment.

Hands should be washed thoroughly after application.

Active ingredient

Podophyllotoxin

Podophyllotoxin is a metaphase inhibitor in dividing cells binding to at least one binding site on tubulin. Binding prevents tubulin polymerisation required for microtubule assembly. At higher concentrations, podophyllotoxin also inhibits nucleoside transport through the cell membrane.

Read more about Podophyllotoxin

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