Bulimia nervosa

Indication for Fluoxetine

Population group: Suitable for both men and women, only adults (18 years old or older)
Therapeutic intent: Adjunct - intent

Fluoxetine is indicated as a complement of psychotherapy for the reduction of binge-eating and purging activity.

For this indication, competent medicine agencies globally authorize below treatments:

60 mg once daily

For: Adults (18-64) Elders (65+)

Dosage regimens

Oral, 60 milligrams, once daily, over the duration of 3 months.

Detailed description

A dose of 60mg/day is recommended. Long-term efficacy (more than 3 months) has not been demonstrated in bulimia nervosa.

Withdrawal symptoms seen on discontinuation of fluoxetine

Abrupt discontinuation should be avoided. When stopping treatment with fluoxetine the dose should be gradually reduced over a period of at least one to two weeks in order to reduce the risk of withdrawal reactions. If intolerable symptoms occur following a decrease in the dose or upon discontinuation of treatment, then resuming the previously prescribed dose may be considered. Subsequently, the physician may continue decreasing the dose, but at a more gradual rate.

Dosage considerations

Fluoxetine may be administered as a single or divided dose, during or between meals.

Active ingredient

Fluoxetine is a selective inhibitor of serotonin reuptake, and this probably accounts for the mechanism of action. Fluoxetine has practically no affinity to other receptors such as α1, α2, and β-adrenergic; serotonergic; dopaminergic; histaminergic1; muscarinic; and GABA receptors.

Read more about Fluoxetine

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