Resistant ascites

Active Ingredient: Spironolactone

Indication for Spironolactone

Population group: only minors (0 - 18 years old)
Therapeutic intent: Curative procedure

For this indication, competent medicine agencies globally authorize below treatments:

1-7 mg/kg daily

For:

Dosage regimens

Oral, in total between 1 milligrams spironolactone per kilogram of body weight and 7 milligrams spironolactone per kilogram of body weight, daily to meals. The maximum allowed total dose is 7 milligrams spironolactone per kilogram of body weight daily.

Detailed description

Up to a maximum of 7 mg/kg daily may be used.

Neonates should only be treated under guidance of a paediatric specialist. There is limited paediatric data available.

Dosage considerations

Spironolactone should be taken together with a meal.

1-9 mg/kg daily

For:

Dosage regimens

Oral, in total between 1 milligrams spironolactone per kilogram of body weight and 9 milligrams spironolactone per kilogram of body weight, daily to meals. The maximum allowed total dose is 9 milligrams spironolactone per kilogram of body weight daily.

Detailed description

Infant or Child 1 month to 18 years: up to a maximum of 9 mg/kg daily (total maximum 400 mg daily) may be used.

Neonates, children and adolescents should only be treated under guidance of a paediatric specialist. There is limited paediatric data available.

Dosage considerations

Spironolactone should be taken together with a meal.

Active ingredient

Spironolactone

Spironolactone, as a competitive aldosterone antagonist, increases sodium excretion whilst reducing potassium loss at the distal renal tubule. It has a gradual and prolonged action.

Read more about Spironolactone

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