Chloroquine-resistant falciparum malaria

Indication for Doxycycline

Population group: Suitable for both men and women, only adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

200 mg in 2 divided doses daily

Route of admnistration

Oral

Defined daily dose

200 - 200 mg

Dosage regimen

From 100 To 100 mg 2 time(s) per day every day for 7 day(s)

Detailed description

200 mg daily for at least 7 days. Due to the potential severity of the infection, a rapid-acting schizonticide such as quinine should always be given in conjunction with doxycycline; quinine dosage recommendations vary in different areas.

Dosage considerations

Doxycycline tablets are administered by drinking a suspension of the tablets in a small amount of water. This should be done in the sitting or standing position and well before retiring at night to reduce the risk of oesophageal irritation and ulceration. If gastric irritation occurs, it is recommended that doxycycline be given with food or milk. Studies indicate that the absorption of doxycycline is not notably influenced by simultaneous ingestion of food or milk.

Active ingredient

Doxycycline is primarily bacteriostatic and is believed to exert its antimicrobial effect by the inhibition of protein synthesis.

Read more about Doxycycline

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