Heterozygous familial hypercholesterolaemia

Active Ingredient: Pravastatin

Indication for Pravastatin

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Children and adolescents (8-18 years of age) with heterozygous familial hypercholesterolaemia.

For this indication, competent medicine agencies globally authorize below treatments:

10-40 mg once daily

Route of admnistration

Oral

Defined daily dose

40 - 40 mg

Dosage regimen

From 40 To 40 mg once every day

Detailed description

The recommended dose range is 10–20 mg once daily between 8 and 13 years of age as doses greater than 20 mg have not been studied in this population and 10-40 mg daily between 14 and 18 years of age.

Dosage considerations

Pravastatin sodium is administered orally once daily preferably in the evening with or without food.

Active ingredient

Pravastatin

Pravastatin is a competitive inhibitor of 3-hydroxy–3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme catalyzing the early rate limiting step in cholesterol biosynthesis, and produces its lipid lowering effect in two ways.

Read more about Pravastatin

Related medicines

Develop a tailored medication plan for your case, considering factors such as age, gender, and health history

Ask the Reasoner

Liability Disclaimer : RxReasoner has utilized reasonable care in providing content and services that are accurate, complete and up to date. However, RxReasoner does not accept any responsibility or liability about it. The content and services of RxReasoner are for informational purposes only and they are not intended to be a substitute for the knowledge, expertise, skill, and judgment of physicians, pharmacists, nurses, or other healthcare professionals involved in patient care. RxReasoner offers no medical advice. Users are responsible for the use of the provided content. A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. The absence of an indication or treatment should not roule out the existence of other appropriate medications. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition or medicament. RxReasoner is not liable for any damages allegedly sustained arising out of the use of its content and services.