Chemical formula: C₂₃H₃₆O₇ Molecular mass: 424.528 g/mol PubChem compound: 54687
Pravastatin is a competitive inhibitor of 3-hydroxy–3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme catalyzing the early rate limiting step in cholesterol biosynthesis, and produces its lipid lowering effect in two ways.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C10AA03 | Pravastatin | C Cardiovascular system → C10 Lipid modifying agents → C10A Lipid modifying agents, plain → C10AA HMG CoA reductase inhibitors |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| PRAVASTATIN SODIUM Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| PRAVACHOL Tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Pravastatin is an active ingredient of these brands:
United States (US)
Australia (AU)Austria (AT)
Croatia (HR)
Cyprus (CY)
Ecuador (EC)
Estonia (EE)
France (FR)
Germany (DE)
Hong Kong (HK)
Ireland (IE)
Israel (IL)
Italy (IT)
Lithuania (LT)
Netherlands (NL)
New Zealand (NZ)
Poland (PL)
Singapore (SG)
South Africa (ZA)Spain (ES)
Turkey (TR)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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