Alcohol abstinence support

Active Ingredient: Naltrexone

Indication for Naltrexone

Population group: only adults (18 - 65 years old)
Therapeutic intent: Adjunct - intent

Naltrexone is used as part of a comprehensive programme of treatment against alcoholism to reduce the risk of relapse, as support treatment in abstinence and to reduce the craving for alcohol.

For this indication, competent medicine agencies globally authorize below treatments:

50 mg once daily

For:

Dosage regimens

Regimen A: Oral, 50 milligrams naltrexone, once daily.

Regimen B: Oral, 100 milligrams naltrexone, one dose, over the duration of 2 days. Afterwards, oral, 100 milligrams naltrexone, one dose, over the duration of 2 days. Afterwards, oral, 150 milligrams naltrexone, one dose, over the duration of 3 days.

Detailed description

Treatment with naltrexone should according to national guidelines only be initiated and monitored by physicians experienced with the treatment of alcohol-addicted patients.

The treatment should be initiated with low doses of naltrexone according to the treatment induction schedule.

Higher doses than 150 mg even for only one day may result in an increase in side effects and are therefore not recommended.

The recommended dose of naltrexone hydrochloride in adults is 50 mg per day.

Active ingredient

Naltrexone

Naltrexone is an orally used, long acting specific opioid antagonist. Naltrexone binds competitively to receptors which are located in the central and peripheral nervous system and hence blocks the access for exogenously administered opioids.

Read more about Naltrexone

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