Active Ingredient: Binimetinib
Binimetinib in combination with encorafenib is indicated for the treatment of adult patients with unresectable or metastatic melanoma with a BRAF V600 mutation.
For this indication, competent medicine agencies globally authorize below treatments:
Oral
90 - 90 mg
From 45 To 45 mg 2 time(s) per day every day
The recommended dose of binimetinib is 45 mg twice daily, corresponding to a total daily dose of 90 mg approximately 12 hours apart.
Treatment should continue until the patient no longer derives benefit or the development of unacceptable toxicity.
If a dose of binimetinib is missed, it should not be taken if it is less than 6 hours until the next dose is due.
In case of vomiting after administration of binimetinib, the patient should not re-take the dose and should take the next scheduled dose.
They may be taken with or without food.
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