Chronic glaucoma

Active Ingredient: Apraclonidine

Indication for Apraclonidine

Population group: only adults (18 years old or older)

Apraclonidine is indicated for short-term adjunctive therapy of chronic glaucoma in patients on maximally tolerated medical therapy who require additional intraocular pressure (IOP) reduction to delay laser treatment or glaucoma surgery.

For this indication, competent medicine agencies globally authorize below treatments:

3 drops in 3 divided doses daily

Route of admnistration


Defined daily dose

3 - 3 {drops}

Dosage regimen

From 1 To 1 {drops} 3 time(s) per day every day

Detailed description

One drop of apraclonidine should be instilled into the affected eye(s) three times per day (t.i.d.). Since apraclonidine will be used with other ocular glaucoma therapies, an approximate five minute interval between instillation of each medication should be observed to prevent washout of the previous dose. Eye ointments should be administered last.

If, for any reason, the drop of apraclonidine does not remain in the eye, then the patient should repeat the dose by placing another drop in the eye. The maximum recommended duration of therapy is one month due to loss of effect over time (tachyphylaxis). However, some patients may benefit from treatment with apraclonidine for longer periods.

Active ingredient


Apraclonidine is an α2-adrenergic receptor agonist and a weak α1-adrenergic receptor agonist. It is used for the prevention and treatment of postsurgical intraocular pressure elevation.

Read more about Apraclonidine

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