Apraclonidine Other names: Lopidine

Chemical formula: C₉H₁₀Cl₂N₄  Molecular mass: 245.109 g/mol  PubChem compound: 2216

Active ingredient description

Apraclonidine is an α2-adrenergic receptor agonist and a weak α1-adrenergic receptor agonist. It is used for the prevention and treatment of postsurgical intraocular pressure elevation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
S01EA03 Apraclonidine S Sensory organs → S01 Ophthalmologicals → S01E Antiglaucoma preparations and miotics → S01EA Sympathomimetics in glaucoma therapy
Discover more medicines within S01EA03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
IOPIDINE Eye drops, solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 66711-21-5
DrugBank Drug: DB00964
PubChem Compound: 2216
RxNorm Ingredient: 14845
SNOMED-CT Concept: 391786008
Apraclonidine (substance)
UNII Identifier: 843CEN85DI

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