Guillain Barrรฉ syndrome

Active Ingredient: Immunoglobulins, normal human, IV

Indication for Immunoglobulins, normal human, IV

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Therapeutic intent: Curative procedure

Immunomodulation in adults, and children and adolescents in Guillain Barrรฉ syndrome.

For this indication, competent medicine agencies globally authorize below treatments:

0.4 g/kg/day over 5 days


Dosage regimens

Intravenous, 0.4 grams immunoglobulins, normal human, IV per kilogram of body weight, once daily, over the duration of 5 days.

Detailed description

0.4 g/kg/day over 5 days (possible repeat of dosing in case of relapse).

Dosage considerations

Human normal immunoglobulin should be infused intravenously at an initial rate of 0.5 ml/kgBW/hr for 30 minutes. If well tolerated, the rate of administration may gradually be increased to a maximum of 6 ml/kgBW/hr.

Clinical data obtained from a limited number of patients also indicate that adult PID patients may tolerate an infusion rate of up to 8 ml/kg BW/hr.

Any infusion-related adverse events should be treated by lowering infusion rates or by stopping the infusion.

Active ingredient

Immunoglobulins, normal human, IV

Human normal immunoglobulin contains mainly immunoglobulin G (IgG) with a broad spectrum of antibodies against infectious agents. The mechanism of action in indications other than replacement therapy is not fully elucidated, but includes immunomodulatory effects.

Read more about Immunoglobulins, normal human, IV

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