Active Ingredient: Melphalan
Melphalan in combination with other cytotoxic medicinal products is indicated as reduced intensity conditioning (RIC) treatment prior to allogeneic haematopoietic stem cell transplantation (allo-HSCT) in malignant haematological diseases.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Regimen A
Intravenous, 140 milligrams melphalan per square meter of body surface, one dose.
Regimen B
Intravenous, 70 milligrams melphalan per square meter of body surface, once daily, over the duration of 2 days.
The recommended dose is 140 mg/m² as a single daily infusion or 70 mg/m² once daily for two consecutive days.
For:
Intravenous, 140 milligrams melphalan per square meter of body surface, one dose.
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