Essential hypertension

Active Ingredient: Losartan

Indication for Losartan

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Treatment of essential hypertension in adults and in children and adolescents 6-18 years of age.

For this indication, competent medicine agencies globally authorize below treatments:

0.7-1.4 mg/kg mg once daily

Route of admnistration

Oral

Defined daily dose

0.7 - 1.4 mg per kg of body weight

Dosage regimen

From 0.7 To 1.4 mg per kg of body weight once every day

Detailed description

6 years to 18 years

The recommended starting dose in patients >20 to <50 kg is 0.7 mg/kg once daily (up to 25 mg total, in exceptional cases where target doses above 25 mg are required, the maximal dose is 50 mg). Dosage should be adjusted according to blood pressure response.

In patients >50 kg, the usual dose is 50 mg once daily. In exceptional cases the dose can be adjusted to a maximum of 100 mg once daily. Doses above 1.4 mg/kg (or in excess of 100 mg) daily have not been studied in paediatric patients.

Losartan is not recommended for use in children below 6 years old due to insufficient data on safety and/or efficacy in these patient groups.

Dosage considerations

Losartan may be administered with or without food.

Active ingredient

Losartan

Losartan is a synthetic oral angiotensin-II receptor (type AT1) antagonist. Antihypertensive activity and suppression of plasma aldosterone concentration are maintained, indicating effective angiotensin II receptor blockade.

Read more about Losartan

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