Losartan Other names: Losartan potassium

Chemical formula: C₂₂H₂₃ClN₆O  Molecular mass: 422.911 g/mol  PubChem compound: 3961

Active ingredient description

Losartan is a synthetic oral angiotensin-II receptor (type AT1) antagonist. Antihypertensive activity and suppression of plasma aldosterone concentration are maintained, indicating effective angiotensin II receptor blockade.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C09CA01 Losartan C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09C Angiotensin II antagonists, plain → C09CA Angiotensin II antagonists, plain
Discover more medicines within C09CA01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
COZAAR Film-coated tablets Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
COZAAR Film-coated tablet FDA, National Drug Code (US) MPI, US: SPL/PLR
COZAAR Powder and solvent for oral suspension Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 114798-26-4
DrugBank Drug: DB00678
KEGG Drug: D08146
PubChem Compound: 3961
RxNorm Ingredient: 52175
SNOMED-CT Concept: 373567002
Losartan (substance)
UNII Identifier: JMS50MPO89
LOSARTAN

Medicines

Losartan is an active ingredient of these brands:

United States (US)

  • COZAAR as LOSARTAN POTASSIUM

  • (combination) HYZAAR as LOSARTAN POTASSIUM

Albania (AL)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

  • COZAAR as LOSARTAN POTASSIUM

  • (combination) HYZAAR as LOSARTAN POTASSIUM

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Italy (IT)

  • LASTAN as LOSARTAN POTASSIUM
  • LORTAAN as LOSARTAN POTASSIUM
  • LOSAPREX as LOSARTAN POTASSIUM
  • NEOLOTAN as LOSARTAN POTASSIUM
  • PRECTEN as LOSARTAN POTASSIUM

  • (combination) FORZAAR as LOSARTAN POTASSIUM
  • (combination) HIZAAR as LOSARTAN POTASSIUM
  • (combination) IPERSART as LOSARTAN POTASSIUM
  • (combination) LOSAZID as LOSARTAN POTASSIUM
  • (combination) LOZID as LOSARTAN POTASSIUM
  • (combination) NEOLOTAN PLUS as LOSARTAN POTASSIUM
  • (combination) PRECTIAZIDE as Losartan potassium

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

  • COZAAR as LOSARTAN POTASSIUM

  • (combination) BICARTIAL as LOSARTAN POTASSIUM
  • (combination) COZAAR XQ as LOSARTAN POTASSIUM
  • (combination) HYZAAR as LOSARTAN POTASSIUM

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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