Active Ingredient: Dacarbazine
For this indication, competent medicine agencies globally authorize below treatments:
Intravenous
250 - 250 mg per m² of body surface area (BSA)
From 250 To 250 mg per m² of body surface area (BSA) once every day for 5 day(s)
For adult soft tissue sarcomas dacarbazine is given in daily doses of 250 mg/m² body surface area i.v. (days 1-5) in combination with doxorubicin every 3 weeks (ADIC regimen).
Doses up to 200 mg/m² may be given as a slow intravenous injection. Larger doses (ranging from 200 to 850 mg/m²) should be administered as an i.v. infusion over 15-30 minutes.
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