Dacarbazine

Chemical formula: C₆H₁₀N₆O  Molecular mass: 182.187 g/mol  PubChem compound: 5351166

Active ingredient description

Dacarbazine is a cytostatic agent. The antineoplastic effect is due to an inhibition of cell growth which is independent of the cell cycle and due to an inhibition of DNA synthesis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
L01AX04 Dacarbazine L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01A Alkylating agents → L01AX Other alkylating agents
Discover more medicines within L01AX04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
DACARBAZINE Powder for solution for injection or infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 4342-03-4
DrugBank Drug: DB00851
KEGG Drug: D00288
PubChem Compound: 5351166
RxNorm Ingredient: 3098
SNOMED-CT Concept: 387441003
Dacarbazine (substance)
UNII Identifier: 7GR28W0FJI
DACARBAZINE

Medicines

Dacarbazine is an active ingredient of these brands:

Brazil (BR)

Estonia (EE)

France (FR)

Lithuania (LT)

Poland (PL)

Romania (RO)

Tunisia (TN)

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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