Endometriosis

Active Ingredient: Linzagolix

Indication for Linzagolix

Population group: women, only adults (18 - 65 years old)
Therapeutic intent: Curative procedure

Linzagolix is indicated in adult women of reproductive age for symptomatic treatment of endometriosis in women with a history of previous medical or surgical treatment for their endometriosis.

For this indication, competent medicine agencies globally authorize below treatments:

200 mg once daily

For:

Dosage regimens

Oral, 200 milligrams linzagolix, once daily.

Detailed description

Linzagolix treatment should be initiated and supervised by a physician experienced in the diagnosis and treatment of endometriosis.

The recommended dose of linzagolix is 200 mg once daily with concomitant hormonal add-back therapy.

Pregnancy must be ruled out prior to initiating treatment with linzagolix.

Linzagolix should preferably be started in the first week of the menstrual cycle and should be taken continuously once daily.

In patients with risk factors for osteoporosis or bone loss, a dual X-ray absorptiometry (DXA) scan is recommended prior to starting linzagolix treatment.

Linzagolix can be taken without interruption. A DXA scan is recommended after 1 year of treatment for all women, and there is a need for continued BMD monitoring thereafter.

Missed dose

If a dose is missed, treatment must be taken as soon as possible and then continued the next day at the usual time.

Active ingredient

Linzagolix

Linzagolix is a selective, non-peptide gonadotropin-releasing hormone (GnRH) receptor antagonist that inhibits endogenous GnRH signalling by binding competitively to GnRH receptors in the pituitary gland, thereby modulating the hypothalamic-pituitary-gonadal axis.

Read more about Linzagolix

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