Hodgkin's disease

Active Ingredient: Dacarbazine

Indication for Dacarbazine

Population group: only adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

375 mg/m² once every 15 days

Route of admnistration

Intravenous

Defined daily dose

375 - 375 mg per m² of body surface area (BSA)

Dosage regimen

From 375 To 375 mg per m² of body surface area (BSA) once every 15 day(s)

Detailed description

Dacarbazine is administered in a daily dose of 375 mg/m² body surface area i.v. every 15 days in combination with doxorubicin, bleomycin and vinblastine (ABVD regimen).

Dosage considerations

Doses up to 200 mg/m² may be given as a slow intravenous injection. Larger doses (ranging from 200 to 850 mg/m²) should be administered as an i.v. infusion over 15-30 minutes.

Active ingredient

Dacarbazine

Dacarbazine is a cytostatic agent. The antineoplastic effect is due to an inhibition of cell growth which is independent of the cell cycle and due to an inhibition of DNA synthesis.

Read more about Dacarbazine

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