Calcitonin is indicated for prevention of acute bone loss due to sudden immobilisation such as in patients with recent osteoporotic fractures.
For this indication, competent medicine agencies globally authorize below treatments:
For: Adults (18-64) Elders (65+)
Regimen A: Intramuscular, 100 international units, divided 1 to 2 times daily, over the duration of 2 to 4 weeks. Afterwards, intramuscular, 50 international units, divided 1 to 2 times daily.
Regimen B: Subcutaneous, 100 international units, divided 1 to 2 times daily, over the duration of 2 to 4 weeks. Afterwards, subcutaneous, 50 international units, divided 1 to 2 times daily.
The recommended dosage is 100 IU daily or 50 IU twice daily administered subcutaneously or intramuscularly. The dose may be reduced to 50 IU daily at the start of remobilisation. The recommended treatment duration is 2 weeks and should not exceed 4 weeks in any case due to the association of the increased risk of malignancies and long term calcitonin use.
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