Zollinger-Ellison syndrome

Active Ingredient: Omeprazole

Indication for Omeprazole

Population group: only adults (18 years old or older)

Treatment of Zollinger-Ellison syndrome.

For this indication, competent medicine agencies globally authorize below treatments:

20-120 mg in 1-2 divided doses daily

Route of admnistration

Oral

Defined daily dose

20 - 120 mg

Dosage regimen

From 10 To 60 mg 2 time(s) per day every day

Detailed description

In patients with Zollinger-Ellison syndrome the dose should be individually adjusted and treatment continued as long as clinically indicated. The recommended initial dose is Omeprazole 60mg daily. All patients with severe disease and inadequate response to other therapies have been effectively controlled and more than 90% of the patients maintained on doses of Omeprazole 20-120mg daily. When dose exceed omeprazole 80mg daily, the dose should be divided and given twice daily.

Dosage considerations

It should be taken in the morning.

60-120 mg in 1-2 divided doses daily

Route of admnistration

Intravenous

Defined daily dose

60 - 120 mg

Dosage regimen

From 30 To 60 mg 2 time(s) per day every day

Loading dose

60 mg

Detailed description

In patients with Zollinger-Ellison Syndrome the recommended initial dose of omeprazole given intravenously is 60 mg daily. Higher daily doses may be required and the dose should be adjusted individually. When doses exceed 60 mg daily, the dose should be divided and given twice daily.

Dosage considerations

Omeprazole is to be administered in an intravenous infusion for 20-30 minutes.

Active ingredient

Omeprazole

Omeprazole, a racemic mixture of two enantiomers reduces gastric acid secretion through a highly targeted mechanism of action. It is a specific inhibitor of the acid pump in the parietal cell. It is rapidly acting and provides control through reversible inhibition of gastric acid secretion with once daily dosing.

Read more about Omeprazole

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