Suppression of recurrences of herpes simplex virus (HSV) infections in immunosuppression

Active Ingredient: Valaciclovir

Indication for Valaciclovir

Population group: only adults (18 years old or older)
Therapeutic intent: Preventive action

Suppression of recurrences of herpes simplex virus (HSV) infections in adult patients with mild or moderate immunosuppression.

For this indication, competent medicine agencies globally authorize below treatments:

1,000 mg in 2 divided doses daily

Route of admnistration

Oral

Defined daily dose

1,000 - 1,000 mg

Dosage regimen

From 500 To 500 mg 2 time(s) per day every day

Detailed description

The dose is 500 mg of valaciclovir twice daily. This dose should be reduced according to creatinine clearance. Treatment should be re-evaluated after 6 to 12 months of therapy.

Dosage considerations

It can be taken with or without food.

Active ingredient

Valaciclovir

Valaciclovir, an antiviral, is the L-valine ester of aciclovir. Valaciclovir is rapidly and almost completely converted in man to aciclovir and valine. Aciclovir is a specific inhibitor of the herpes viruses with in vitro activity against herpes simplex viruses (HSV) type 1 and type 2, varicella zoster virus (VZV), cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and human herpes virus 6 (HHV-6).

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