Valaciclovir

Chemical formula: C₁₃H₂₀N₆O₄  Molecular mass: 324.336 g/mol  PubChem compound: 60773

Active ingredient description

Valaciclovir, an antiviral, is the L-valine ester of aciclovir. Valaciclovir is rapidly and almost completely converted in man to aciclovir and valine. Aciclovir is a specific inhibitor of the herpes viruses with in vitro activity against herpes simplex viruses (HSV) type 1 and type 2, varicella zoster virus (VZV), cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and human herpes virus 6 (HHV-6).

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J05AB11 Valaciclovir J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
Discover more medicines within J05AB11

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
VALTREX Film-coated tablet FDA, National Drug Code (US) MPI, US: SPL/PLR
VALACICLOVIR Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 124832-26-4
DrugBank Drug: DB00577
KEGG Drug: D00398
PubChem Compound: 60773
RxNorm Ingredient: 73645
SNOMED-CT Concept: 96098007
Valaciclovir (substance)
UNII Identifier: MZ1IW7Q79D
VALACYCLOVIR

Medicines

Valaciclovir is an active ingredient of these brands:

United States (US)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Australia (AU)

Austria (AT)

  • VALDACIR as VALACYCLOVIR HYDROCHLORIDE
  • VALTREX as VALACYCLOVIR HYDROCHLORIDE
  • VIROPEL as VALACYCLOVIR HYDROCHLORIDE

Brazil (BR)

  • DAZEK as VALACYCLOVIR HYDROCHLORIDE
  • HERPSTAL as VALACYCLOVIR HYDROCHLORIDE
  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Canada (CA)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Cyprus (CY)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Ecuador (EC)

Estonia (EE)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Finland (FI)

  • FLUSHNIL as VALACYCLOVIR HYDROCHLORIDE
  • VALAVIR as VALACYCLOVIR HYDROCHLORIDE
  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

France (FR)

  • ZELITREX as VALACYCLOVIR HYDROCHLORIDE

Hong Kong (HK)

  • VALAJUB as VALACYCLOVIR HYDROCHLORIDE
  • VALTRA as VALACYCLOVIR HYDROCHLORIDE
  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Ireland (IE)

Israel (IL)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Italy (IT)

  • TALAVIR as VALACYCLOVIR HYDROCHLORIDE
  • ZELITREX as VALACYCLOVIR HYDROCHLORIDE

Japan (JP)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Lithuania (LT)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Mexico (MX)

Netherlands (NL)

  • ZELITREX as VALACYCLOVIR HYDROCHLORIDE

New Zealand (NZ)

Nigeria (NG)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Poland (PL)

  • VACICLOR as VALACYCLOVIR HYDROCHLORIDE
  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Romania (RO)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Singapore (SG)

  • VACICLOR as VALACYCLOVIR HYDROCHLORIDE
  • VALOVIR as VALACYCLOVIR HYDROCHLORIDE
  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.