Chemical formula: C₁₃H₂₀N₆O₄ Molecular mass: 324.336 g/mol PubChem compound: 60773
Valaciclovir, an antiviral, is the L-valine ester of aciclovir. Valaciclovir is rapidly and almost completely converted in man to aciclovir and valine. Aciclovir is a specific inhibitor of the herpes viruses with in vitro activity against herpes simplex viruses (HSV) type 1 and type 2, varicella zoster virus (VZV), cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and human herpes virus 6 (HHV-6).
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| J05AB11 | Valaciclovir | J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| VALTREX Film-coated tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| VALACICLOVIR Film-coated tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Valaciclovir is an active ingredient of these brands:
United States (US)
Australia (AU)Austria (AT)Brazil (BR)Canada (CA)
Cyprus (CY)
Estonia (EE)
Finland (FI)France (FR)
Hong Kong (HK)Israel (IL)
Japan (JP)
Lithuania (LT)
Mexico (MX)Netherlands (NL)
Nigeria (NG)
Romania (RO)
Singapore (SG)South Africa (ZA)
Tunisia (TN)United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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