Valaciclovir

Chemical formula: C₁₃H₂₀N₆O₄  Molecular mass: 324.336 g/mol  PubChem compound: 60773

Therapeutic indications

Valaciclovir is indicated for:

Varicella zoster virus (VZV) infections, herpes zoster, ophthalmic zoster

Population group: only adults (18 years old or older)

Valaciclovir is indicated for the treatment of herpes zoster (shingles) and ophthalmic zoster in immunocompetent adults.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Varicella zoster virus (VZV) infections, herpes zoster, ophthalmic zoster in immunosuppression

Population group: only adults (18 years old or older)

Valaciclovir is indicated for the treatment of herpes zoster (shingles) and ophthalmic zoster in adult patients with mild or moderate immunosuppression.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Herpes labialis

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Herpes labialis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Herpes simplex virus (HSV) infections

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Valaciclovir is indicated:

  • for the treatment and suppression of HSV infections of the skin and mucous membranes including:
    • treatment of first-episode of genital herpes in immunocompetent adults and adolescents.
    • treatment of recurrences of genital herpes in immunocompetent adults and adolescents.
    • suppression of recurrent genital herpes in immunocompetent adults and adolescents.
  • for the treatment and suppression of recurrent ocular HSV infections in immunocompetent adults and adolescents.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Herpes simplex virus (HSV) infections in immunosuppression

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Valaciclovir is indicated:

  • for the treatment and suppression of HSV infections of the skin and mucous membranes including:
    • treatment of first-episode of genital herpes in immunocompetent adults and adolescents and in immunocompromised adults.
    • treatment of recurrences of genital herpes in immunocompetent adults and adolescents, and in immunocompromised adults.
    • suppression of recurrent genital herpes in immunocompetent adults and adolescents and in immunocompromised adults.
  • for the treatment and suppression of recurrent ocular HSV infections in immunocompetent adults and adolescents and in immunocompromised adults.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Suppression of recurrences of herpes simplex virus (HSV) infections

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Suppression of recurrences of herpes simplex virus (HSV) infections in adults and adolescents (≥12 years).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Suppression of recurrences of herpes simplex virus (HSV) infections in immunosuppression

Population group: only adults (18 years old or older)

Suppression of recurrences of herpes simplex virus (HSV) infections in adult patients with mild or moderate immunosuppression.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prophylaxis of cytomegalovirus (CMV) infection and disease

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Prophylaxis of cytomegalovirus (CMV) infection and disease in adults and adolescents (≥12 years).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Valaciclovir is contraindicated in the following cases:

Hypersensitivity to valaciclovir

Valaciclovir allergy

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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Related medicines

Structured Product Labeling (SPL/PLR) 2019: VALTREX Film-coated tablet
Summary of Product Characteristics (SPC) 2016: VALACICLOVIR Film-coated tablet
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