Active Ingredient: Remibrutinib
Remibrutinib is indicated for the treatment of chronic spontaneous urticaria (CSU) in adult patients with inadequate response to H1 antihistamine treatment.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, 25 milligrams remibrutinib, 2 times daily.
The recommended dose of remibrutinib is 25 mg taken orally twice daily, once in the morning and once in the evening.
If a patient misses one or more doses of remibrutinib, the patient should be instructed to take the next dose at its regularly scheduled time. Extra doses of remibrutinib should not be taken to make up for the missed dose or doses.
Prescribers are advised to periodically reassess the need for continued therapy. Consideration should be given to discontinuing treatment in patients who have shown no response after 24 weeks of treatment for CSU.
It is recommended to interrupt remibrutinib for 3 to 7 days before surgery and for 3 to 7 days after surgery depending upon the type of surgery and the risk of bleeding.
No specific dose adjustment is required for elderly patients (aged ≥65 years). Limited data are available on the use of remibrutinib in patients older than 65 years.
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