RHAPSIDO Film-coated tablet Ref.[116560] Active ingredients: Remibrutinib

Source: European Medicines Agency (EU)  Revision Year: 2026  Publisher: Novartis Europharm Limited, Vista Building, Elm Park, Merrion Road, Dublin 4, Ireland

Product name and form

Rhapsido 25 mg film-coated tablets.

Pharmaceutical Form

Film-coated tablet (tablet).

Light yellow, round, curved film-coated tablet with a diameter of 6.7 to 7.6 mm, debossed with "LV" on one side and with the company logo on the other side.

Qualitative and quantitative composition

Each film-coated tablet contains 25 mg remibrutinib.

For the full list of excipients, see section 6.1.

Active Ingredient

Remibrutinib is a selective Bruton's tyrosine kinase (BTK) inhibitor that forms a covalent bond with a cysteine residue in the BTK active site, leading to durable inactivation of BTK. The therapeutic effect of remibrutinib in CSU is achieved through inhibition of mast cell and basophil degranulation, including release of histamine and other proinflammatory mediators, mediated by pathogenic IgE or IgG directed against the FcεR1 or IgE.

List of Excipients

Tablet core:

Mannitol
Microcrystalline cellulose
Copovidone
Croscarmellose sodium
Sodium stearyl fumarate
Sodium lauryl sulfate

Tablet coating:

Polyvinyl alcohol
Macrogol 4000
Talc
Titanium dioxide (E171)
Yellow iron oxide (E172)
Red iron oxide (E172)

Pack sizes and marketing

Rhapsido is supplied in PA/alu/PVC/alu (polyamide/aluminium/polyvinylchloride/aluminium) blisters with aluminium foil backing and is available in packs containing 30, 60 or 180 film-coated tablets.

Not all pack sizes may be marketed.

Marketing authorization holder

Novartis Europharm Limited, Vista Building, Elm Park, Merrion Road, Dublin 4, Ireland

Marketing authorization dates and numbers

EU/1/26/2024/001-003

Drugs

Drug Countries
RHAPSIDO United States

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