Acute hypertensive crisis

Active Ingredient: Diazoxide

Indication for Diazoxide

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

For this indication, competent medicine agencies globally authorize below treatments:

5 mg/Kg

Route of admnistration

Intravenous

Defined daily dose

5 - 5 mg per kg of body weight

Dosage regimen

From 5 To 5 mg per kg of body weight once every day

Detailed description

On the rare occasions that Eudemine injection is indicated for hypertension in children, the dosage should be based on a level of 5 mg per Kg body weight.

A response occurs within five minutes and usually persists for a least four hours. One injection is usually effective, but further injections may be required, particularly in hypertensive crises or in accelerating disease refractory to other hypotensive agents. Up to four ampoules may be given in 24 hours.

Active ingredient

Diazoxide

Diazoxide is a peripheral vasodilator and has qualitatively the same effect on blood vessels as benzothiazine compounds, but the effect is more rapid and profound. Unlike benzothiazines, diazoxide is non-diuretic and causes retention of sodium and water. It causes a prompt increase in blood glucose by a direct inhibitory action on the secretion of insulin by the beta cells in the Islets of Langerhans.

Read more about Diazoxide

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