Diazoxide C₈H₇ClN₂O₂S

Active ingredient description

Diazoxide is a peripheral vasodilator and has qualitatively the same effect on blood vessels as benzothiazine compounds, but the effect is more rapid and profound. Unlike benzothiazines, diazoxide is non-diuretic and causes retention of sodium and water. It causes a prompt increase in blood glucose by a direct inhibitory action on the secretion of insulin by the beta cells in the Islets of Langerhans.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
C02DA01
Diazoxide
C Cardiovascular system → C02 Antihypertensives → C02D Arteriolar smooth muscle, agents acting on → C02DA Thiazide derivatives
Discover more medicines within C02DA01
V03AH01
Diazoxide
V Various → V03 All other therapeutic products → V03A All other therapeutic products → V03AH Drugs for treatment of hypoglycemia
Discover more medicines within V03AH01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Information Source
Document Type
 
EUDEMINE Solution for injection
Medicines & Healthcare Products Regulatory Agency (GB)
Summary of Product Characteristics (SPC)
EUDEMINE Sugar coated tablet
Medicines & Healthcare Products Regulatory Agency (GB)
Summary of Product Characteristics (SPC)
PROGLYCEM Capsule / Suspension
FDA, National Drug Code (US)
Structured Product Labeling (SPL)

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₈H₇ClN₂O₂S
Molecular mass: 230.671 g/mol

External identifiers

CAS Substance: 364-98-7
DrugBank Drug: DB01119
KEGG Drug: D00294
PubChem Compound: 3019
RxNorm Ingredient: 3327
SNOMED-CT Concept: 387328001
Diazoxide (substance)
UNII Identifier: O5CB12L4FN
DIAZOXIDE

Medicines

Diazoxide is an active ingredient of these brands:

United States (US)

Brazil (BR)

Canada (CA)

Estonia (EE)

France (FR)

Netherlands (NL)

United Kingdom (UK)

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.

 
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