Diazoxide

Chemical formula: C₈H₇ClN₂O₂S  Molecular mass: 230.671 g/mol  PubChem compound: 3019

Therapeutic indications

Diazoxide is indicated for:

Leucine-sensitive hypoglycaemia

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Leucine-induced hypoglycemia

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Benign or malignant islet-cell tumours producing large quantities of insulin

Population group: only adults (18 years old or older)

at least one of
Benign islet cell tumor
Malignant tumour of Islets of Langerhans
and additionally Increased insulin level

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Hypoglycaemia

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Hypoglycaemia

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Acute hypertensive crisis

Population group: only adults (18 years old or older)

Diazoxide is used particularly for the emergency treatment of acute hypertensive crises, especially those occurring in association with acute hypertensive encephalopathy, congestive heart failure, acute glomerular nephitis, eclampsia or pre-eclampsia.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Severe hypertension

Population group: only adults (18 years old or older)

Diazoxide is indicated for the control of severe hypertension associated with renal disease. In hypertensive patients requiring such diagnostic procedures as renal biopsy, arteriography or cardiac catheterisation, diazoxide injection may be given to facilitate the procedure and reduce the danger of haemorrhage due to hypertension. Diazoxide injection is also indicated in patients who have failed to respond to other hypotensive agents.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Acute hypertensive crisis

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Hypertensive crisis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Diazoxide is contraindicated in the following cases:

Hypersensitivity to diazoxide

Diazoxide allergy

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