Duodenal ulcer

Active Ingredient: Famotidine

Indication for Famotidine

Population group: only adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

20-40 mg once daily

Route of admnistration


Defined daily dose

20 - 40 mg

Dosage regimen

From 20 To 40 mg once every day

Loading dose

40 mg

Maintenance dose

20 mg

Detailed description

Initial treatment

The recommended dose of famotidine is 40 mg per day, given at night. Treatment should be given for 4 to 8 weeks, but the duration of treatment may be shortened if endoscopy shows that the ulcer has healed. In most cases of duodenal ulcers, healing occurs within 4 weeks with this treatment regimen.

In patients in whom the ulcer has not fully healed after 4 weeks, treatment should be continued for another 4 weeks.

Maintenance treatment

To prevent recurrence of duodenal ulcer, it is recommended to continue treatment with 20 mg per day, administered at night. This dosage regimen has been effectively continued in 1-year clinical trials.

Dosage considerations

Before bedtime.

Active ingredient


Famotidine is a potent competitive H2-receptor antagonist. Famotidine has a rapid onset of action and, at the recommended doses, has a long duration of action and is highly effective at relatively low blood concentrations.

Read more about Famotidine

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