Active Ingredient: Spironolactone
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, between 100 milligrams spironolactone and 400 milligrams spironolactone, once daily to meals.
After the diagnosis of hyperaldosteronism has been established by more definitive testing procedures, spironolactone may be administered in doses of 100 mg to 400 mg daily in preparation for surgery. For patients who are considered unsuitable for surgery, Spironolactone may be employed for long term maintenance therapy at the lowest effective dose determined for the individual patient.
It is recommended that treatment is started with the lowest dose and titrated upwards as required to achieve maximum benefit. Care should be taken in severe hepatic and renal impairment which may alter spironolactone metabolism and excretion.
Spironolactone should be taken together with a meal.
For:
Oral, in total between 1 milligrams spironolactone per kilogram of body weight and 9 milligrams spironolactone per kilogram of body weight, daily to meals. The maximum allowed total dose is 9 milligrams spironolactone per kilogram of body weight daily.
Infant or Child 1 month to 18 years: up to a maximum of 9 mg/kg daily (total maximum 400 mg daily) may be used.
Treatment should only be taken under the guidance of a specialist paediatrician. There is limited paediatric data available.
Spironolactone should be taken together with a meal.
For:
Oral, in total between 1 milligrams spironolactone per kilogram of body weight and 7 milligrams spironolactone per kilogram of body weight, daily to meals. The maximum allowed total dose is 7 milligrams spironolactone per kilogram of body weight daily.
Up to a maximum of 7 mg/kg daily may be used.
Neonates should only be treated under guidance of a paediatric specialist. There is limited paediatric data available.
Spironolactone should be taken together with a meal.
Liability Disclaimer : RxReasoner has utilized reasonable care in providing content and services that are accurate, complete and up to date. However, RxReasoner does not accept any responsibility or liability about it. The content and services of RxReasoner are for informational purposes only and they are not intended to be a substitute for the knowledge, expertise, skill, and judgment of physicians, pharmacists, nurses, or other healthcare professionals involved in patient care. RxReasoner offers no medical advice. Users are responsible for the use of the provided content. A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. The absence of an indication or treatment should not roule out the existence of other appropriate medications. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition or medicament. RxReasoner is not liable for any damages allegedly sustained arising out of the use of its content and services.