Ilaris 150mg powder for solution for injection (2011)
Active ingredients: Canacinumab
Product Name and Form
Ilaris 150 mg powder for solution for injection.
Powder for solution for injection.
The powder is white.
Qualitative and Quantitative Composition
One vial contains 150 mg of canakinumab*.
After reconstitution, each ml of solution contains 150 mg canakinumab.
* fully human monoclonal antibody produced in mouse hybridoma Sp2/0 cells by recombinant DNA technology
For a full list of excipients, see section 6.1.
Canakinumab is a human monoclonal anti-human interleukin-1 beta (IL-1 beta) antibody of the IgG1/κ isotype. Canakinumab binds with high affinity specifically to human IL-1 beta and neutralises the biological activity of human IL-1 beta by blocking its interaction with IL-1 receptors, thereby preventing IL-1 beta-induced gene activation and the production of inflammatory mediators.
Histidine hydrochloride monohydrate
Pack sizes and Marketing
150 mg of powder for solution for injection in a vial (type I glass) with a stopper (coated chlorobutyl rubber) and flip-off cap (aluminium).
Packs containing 1 vial or multipacks containing 4 (4x1) vials.
Not all pack sizes may be marketed.
Novartis Europharm Limited