XAGRID Capsule (2018)
Active ingredients: Anagrelide
Product Name and Form
Xagrid 0.5 mg hard capsules.
An opaque white hard capsule imprinted with S 063.
Qualitative and Quantitative Composition
Each hard capsule contains 0.5 mg anagrelide (as anagrelide hydrochloride).
Excipient(s) with known effect: Each hard capsule contains lactose monohydrate (53.7 mg) and anhydrous lactose (65.8 mg).
For the full list of excipients, see section 6.1.
Anagrelide is an inhibitor of cyclic AMP phosphodiesterase III and suppress expression of transcription factors including GATA-1 and FOG-1 required for megakaryocytopoiesis, ultimately leading to reduced platelet production.
Cellulose, microcrystalline (E460)
Titanium dioxide (E171)
Strong ammonium solution
Potassium hydroxide (E525)
Black iron oxide (E172)
Pack sizes and Marketing
High-density polyethylene (HDPE) bottles with child-resistant closures and desiccant containing 100 capsules.
Shire Pharmaceuticals Ireland Limited, Block 2 & 3 Miesian Plaza, 50 – 58 Baggot Street Lower, Dublin 2, Ireland
Date of first authorisation: 16 November 2004
Date of latest renewal: 16 November 2014