ELIQUIS Film-coated tablets (2018)
Active ingredients: Apixaban
Product Name and Form
Eliquis 2.5 mg film-coated tablets.
Film-coated tablet (tablet).
Yellow, round tablets debossed with 893 on one side and 2 1⁄2 on the other side.
Qualitative and Quantitative Composition
Each film-coated tablet contains 2.5 mg apixaban.
Excipients with known effect: Each 2.5 mg film-coated tablet contains 51.43 mg lactose (see section 4.4).
For the full list of excipients, see section 6.1.
Apixaban is a potent, oral, reversible, direct and highly selective active site inhibitor of factor Xa. It does not require antithrombin III for antithrombotic activity. Apixaban inhibits free and clot-bound factor Xa, and prothrombinase activity. By inhibiting factor Xa, apixaban prevents thrombin generation and thrombus development.
Microcrystalline cellulose (E460)
Magnesium stearate (E470b)
Titanium dioxide (E171)
Yellow iron oxide (E172)
Pack sizes and Marketing
Alu-PVC/PVdC blisters. Cartons of 10, 20, 60, 168 and 200 film-coated tablets.
Alu PVC/PVdC perforated unit dose blisters of 60x1 and 100x1 film-coated tablets.
Not all pack sizes may be marketed.
Bristol-Myers Squibb/Pfizer EEIG, Uxbridge Business Park, Sanderson Road, Uxbridge, Middlesex, UB8 1DH, United Kingdom
Date of first authorisation: 18 May 2011
Date of latest renewal: 14 January 2016