Apixaban

Active ingredient description

Apixaban is a potent, oral, reversible, direct and highly selective active site inhibitor of factor Xa. It does not require antithrombin III for antithrombotic activity. Apixaban inhibits free and clot-bound factor Xa, and prothrombinase activity. By inhibiting factor Xa, apixaban prevents thrombin generation and thrombus development.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
B01AF02
Apixaban
B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AF Direct factor Xa inhibitors
Discover more medicines within B01AF02

Medicines

Apixaban is the active ingredient of these drugs:

Drug
Countries
ABATIXENT

Lithuania

ELIQUIS

Australia Austria Brazil Canada Cyprus

ELIXTRA

Tunisia

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
ELIQUIS Film-coated tablets
Summary of product characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

3Z9Y7UWC1J - APIXABAN

CAS registry number

503612-47-3 - apixaban

SNOMED-CT

698090000 - Apixaban (substance)

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