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Apixaban

Description

Apixaban is a potent, oral, reversible, direct and highly selective active site inhibitor of factor Xa. It does not require antithrombin III for antithrombotic activity. Apixaban inhibits free and clot-bound factor Xa, and prothrombinase activity. By inhibiting factor Xa, apixaban prevents thrombin generation and thrombus development.

ATC Classification

Code
Title
Category
B01AF02
Apixaban
B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AF Direct factor Xa inhibitors

Trade names

Trade name
Countries
ELIQUIS

Australia Austria Canada Cyprus Netherlands

Product Monographs

Monograph
Type
Country
ELIQUIS Film-coated tablets
MPI, EU: SmPC

2D Molecule Structure

Unique Ingredient Identifier (UNII)

3Z9Y7UWC1J - APIXABAN

CAS Registry Number

503612-47-3 - apixaban

SNOMED-CT

698090000 - Apixaban (substance)

 
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