Apixaban

Active ingredient description

Apixaban is a potent, oral, reversible, direct and highly selective active site inhibitor of factor Xa. It does not require antithrombin III for antithrombotic activity. Apixaban inhibits free and clot-bound factor Xa, and prothrombinase activity. By inhibiting factor Xa, apixaban prevents thrombin generation and thrombus development.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AF Direct factor Xa inhibitors
Discover more medicines within B01AF02

Medicines

$substanceName is the active ingredient of these drugs:

Drug
Countries

Ecuador Estonia Lithuania Poland

Estonia

Estonia

Ecuador

Australia Austria Brazil Canada Cyprus

Tunisia

Ecuador

Ecuador

Poland

South Africa

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Molecular mass: 459.497 g/mol

External identifiers

CAS Substance: 503612-47-3
DrugBank Drug: DB06605
KEGG Drug: D03213
RxNorm Ingredient: 1364430
SNOMED-CT Concept: 698090000
Apixaban (substance)
UNII Identifier: 3Z9Y7UWC1J
APIXABAN