AZATHIOPRINE / SANDOZ Film-coated tablets

Active ingredients: Azathioprine

Product name and form

Azathioprine 25 mg film-coated tablets.

Pharmaceutical Form

Film-coated tablet.

White to yellowish-white film-coated tablet, biconvex, no score-line.

Qualitative and quantitative composition

One film-coated tablet contains 25 mg azathioprine.

Excipient(s) with known effect: Lactose

For the full list of excipients, see section 6.1.

Active Ingredient

Azathioprine is a pro-drug of 6-mercaptopurine (6-MP). 6-MP is inactive but acts as a purine antagonist and requires cellular uptake and intracellular anabolism to thioguanine nucleotides (TGNs) for immunosuppression. The TGNs and other metabolites (e.g. 6-methyl-mecaptopurine ribonucleotides) inhibit de novo purine synthesis and purine nucleotide interconversions.

List of Excipients


Lactose monohydrate
Maize starch
Colloidal silicon dioxide
Magnesium stearate


Microcrystalline cellulose
Polyoxyl 8 stearate

Colouring agent:

titanium dioxide (E171)

Pack sizes and marketing

The film-coated tablets are packed in either polypropylene-aluminium blister or PVC/PVDC-aluminium blister in a carton box.

The pack contains 20, 28, 30, 50, 90 or 100 film-coated tablets.

Not all pack sizes may be marketed.

Marketing Authorization Holder
Authorization Dates

Sandoz Limited, Frimley Business Park, Frimley, Camberley, Surrey, GU16 7SR, United Kingdom


Marketing authorization number:

PL 04416/1247