Azathioprine C₉H₇N₇O₂S
Active ingredient description
Azathioprine is a pro-drug of 6-mercaptopurine (6-MP). 6-MP is inactive but acts as a purine antagonist and requires cellular uptake and intracellular anabolism to thioguanine nucleotides (TGNs) for immunosuppression. The TGNs and other metabolites (e.g. 6-methyl-mecaptopurine ribonucleotides) inhibit de novo purine synthesis and purine nucleotide interconversions.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Structural formula
Chemical formula: C₉H₇N₇O₂S
Molecular mass: 277.263 g/mol
3D molecular structure
External identifiers
Medicines
Azathioprine is an active ingredient of these brands:
Austria (AT)
Brazil (BR)
Canada (CA)
Estonia (EE)
Finland (FI)
France (FR)
Italy (IT)
Mexico (MX)
Netherlands (NL)
Romania (RO)
Turkey (TR)
While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.
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