Active ingredients: Azathioprine
Imuran Tablets 25 mg.
Orange, round, biconvex, film-coated tablets, unscored, branded ‘IM 2’ and containing 25 mg Azathioprine BP in each tablet
Each tablet contains 25 mg of the active substance azathioprine.
Excipient(s) with known effect: Each 25 mg tablet contains 37 mg lactose monohydrate.
For the full list of excipients, see section 6.1.
Azathioprine is a pro-drug of 6-mercaptopurine (6-MP). 6-MP is inactive but acts as a purine antagonist and requires cellular uptake and intracellular anabolism to thioguanine nucleotides (TGNs) for immunosuppression. The TGNs and other metabolites (e.g. 6-methyl-mecaptopurine ribonucleotides) inhibit de novo purine synthesis and purine nucleotide interconversions.
Polyethylene glycol 400
Titanium dioxide (E171)
Iron oxide, yellow (E172)
Iron oxide, red (E172)
Blister strips in a pack.
Pack sizes: 28, 30, 56, 60 and 100 tablets.
Aspen Pharma Trading Limited, 3016 Lake Drive, Citywest Business Campus, Dublin 24, Ireland
20 March 1992