Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2019 Publisher: The Boots Company PLC, 1 Thane Road West, Nottingham, NG2 3AA Trading as: BCM
Oxymetazoline hydrochloride is a sympathomimetic amine having vasoconstrictor properties which are utilised in the relief of nasal congestion.
Oxymetazoline enters tissues rapidly and local vasoconstriction is normally achieved within 5-10 minutes of intranasal administration. The full effect lasts for 5-6 hours and then gradually subsides over the next 6 hours. Plasma half-life is 5-8 days with 30% of any absorbed drug being excreted in the urine unchanged and 10% being excreted in the faeces.
There are no preclinical data of relevance to the prescriber which are additional to that already included.
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