HUMIRA 20mg Solution for injection in pre-filled syringe (2018)
Active ingredients: Adalimumab
Product Name and Form
Humira 20 mg solution for injection in pre-filled syringe.
Solution for injection. (injection)
Clear, colourless solution.
Qualitative and Quantitative Composition
Each 0.2 ml single dose pre-filled syringe contains 20 mg of adalimumab.
Adalimumab is a recombinant human monoclonal antibody produced in Chinese Hamster Ovary cells.
For the full list of excipients, see section 6.1.
Adalimumab binds specifically to TNF and neutralizes the biological function of TNF by blocking its interaction with the p55 and p75 cell surface TNF receptors. Adalimumab also modulates biological responses that are induced or regulated by TNF, including changes in the levels of adhesion molecules responsible for leukocyte migration (ELAM-1, VCAM-1, and ICAM-1 with an IC50 of 0.1-0.2 nM).
Water for injections
Pack sizes and Marketing
Humira 20 mg solution for injection in single-use pre-filled syringe (type I glass) with a plunger stopper (bromobutyl rubber) and a needle with a needle shield (thermoplastic elastomer).
Packs of: 2 pre-filled syringes (0.2 ml sterile solution), each with 1 alcohol pad, in a blister.
AbbVie Deutschland GmbH & Co. KG, Knollstrasse, 67061 Ludwigshafen, Germany
Date of first authorisation: 08 September 2003
Date of latest renewal: 08 September 2008