HUMULIN I Suspension for injection in a vial (2019)
Active ingredients: Insulin (human)
Product Name and Form
Humulin I (Isophane) 100 IU/ml suspension for injection in vial.
A suspension for injection in a vial.
Humulin I is a sterile suspension of a white, crystalline precipitate of isophane human insulin in an isotonic phosphate buffer.
Qualitative and Quantitative Composition
1 ml contains 100 IU insulin human (produced in E. coli by recombinant DNA technology).
One vial contains 10 ml equivalent to 1000 IU of isophane insulin.
For a full list of excipients, see section 6.1.
The blood glucose lowering effect of insulin is due to the facilitated uptake of glucose following binding of insulin to receptors on muscle and fat cells and to the simultaneous inhibition of glucose output from the liver.
Dibasic sodium phosphate 7H2O
Water for injections
The following may be used to adjust pH; hydrochloric acid and/or sodium hydroxide.
Pack sizes and Marketing
10 ml of suspension in a vial (type I glass) with a stopper (rubber) sealed with a seal (aluminium) combined with a flip top (plastic). Pack size 1 or 2 or 5 (5 × 1). Not all pack sizes may be marketed.
Eli Lilly and Company Limited, Lilly House, Priestley Road, Basingstoke, Hampshire RG24 9NL
30 July 2019