Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2022 Publisher: Galderma (UK) Limited, Meridien House, 69-71 Clarendon Road, Watford, Herts, WD17 1DS, UK
Pharmacotherapeutic group: Anti-acne preparations for topical use
ATC Code: D10AE01
Benzoyl peroxide is an established and effective keratolytic agent with antibacterial properties. It has been shown to be effective in reducing the local population of Cutibacterium acnes leading to a reduction in the production of irritant fatty acids in the sebaceous glands.
Not applicable. Acnecide is a topical preparation.
In animal studies by the cutaneous route, benzoyl peroxide is associated with a minimal to moderate skin irritation potential including erythema and oedema. Phototoxic and photoallergic reactions have been reported for benzoyl peroxide therapy.
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