Source: European Medicines Agency (EU) Revision Year: 2026 Publisher: Eli Lilly Nederland B.V., Orteliuslaan 1000, 3528 BD Utrecht, The Netherlands
ADCIRCA 20 mg film-coated tablets.
| Pharmaceutical Form |
|---|
|
Film-coated tablet (tablet). Orange and almond shaped film-coated tablets of 12.09 mm x 7.37 mm, marked "4467" on one side. |
Each film-coated tablet contains 20 mg tadalafil.
Excipient with known effect:
Each film-coated tablet contains 233 mg lactose (as monohydrate).
For the full list of excipients, see section 6.1.
| Active Ingredient |
|---|
|
Tadalafil is a selective, reversible inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). When sexual stimulation causes the local release of nitric oxide, inhibition of PDE5 by tadalafil produces increased levels of cGMP in the corpus cavernosum. This results in smooth muscle relaxation and inflow of blood into the penile tissues, thereby producing an erection. The effect of PDE5 inhibition on cGMP concentration in the corpus cavernosum is also observed in the smooth muscle of the prostate, the bladder and their vascular supply. The resulting vascular relaxation increases blood perfusion which may be the mechanism by which symptoms of benign prostatic hyperplasia are reduced. |
| List of Excipients |
|---|
|
Tablet core: Lactose monohydrate Film-coat: Lactose monohydrate |
Aluminium/PVC/PE/PCTFE blisters in cartons of 28 and 56 film-coated tablets.
Not all packs sizes may be marketed.
Eli Lilly Nederland B.V., Orteliuslaan 1000, 3528 BD Utrecht, The Netherlands
EU/1/08/476/005-006
Date of first authorisation: 1 October 2008
Date of latest renewal: 22 May 2013
| Drug | Countries | |
|---|---|---|
| ADCIRCA | Austria, Australia, Canada, Germany, Estonia, Spain, France, Croatia, Ireland, Italy, Japan, Lithuania, Netherlands, New Zealand, Poland, United Kingdom, United States |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.