ANASCORP Powder for solution for injection Ref.[10383] Active ingredients:

For Intravenous use only.

Initiate treatment with ANASCORP as soon as possible after scorpion sting in patients who develop clinically important signs of scorpion envenomation, including but not limited to loss of muscle control, roving or abnormal eye movements, slurred speech, respiratory distress, excessive salivation, frothing at the mouth and vomiting (2).

Initial Dose: 3 vials

• The initial dose of ANASCORP is 3 vials.
• Reconstitute the contents of each vial with 5 milliliters of sterile normal saline (0.9% NaCl) and mix by continuous gentle swirling.
• Combine the contents of the reconstituted vials promptly and further dilute to a total volume of 50 milliliters with sterile normal saline (0.9% NaCl).
• Inspect the solution visually for particulate matter and discoloration prior to administration. Do not use if turbid.
• Infuse intravenously over 10 minutes.
• Monitor patient closely during and up to 60 minutes following the completion of infusion to determine if clinically important signs of envenomation have resolved.
• Discard partially used vials.

Additional Dosing:

• Additional doses may be used if needed.
• Infuse one vial at a time at intervals of 30 to 60 minutes.
• Reconstitute the contents with 5 milliliters of sterile normal saline (0.9% NaCl) and mix by continuous gentle swirling.
• Further dilute to a total volume of 50 milliliters with sterile normal saline (0.9% NaCl). Inspect the solution visually for particulate matter or discoloration prior to administration.
• Infuse intravenously over 10 minutes.
• Monitor patient closely during and up to 60 minutes following the completion of infusion to determine if clinically important signs of envenomation have resolved.
• Discard partially used vials.

Store at room temperature (up to 25°C (77°F)). Brief temperature excursions are permitted up to 40°C (104°F).

DO NOT FREEZE.

Discard partially used vials.