ANQUIL Tablet Ref.[27601] Active ingredients: Benperidol

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2021  Publisher: Neon Healthcare Limited, Mill Studio Business Centre, Crane Mead, Ware, Hertfordshire, SG12 9PY, UK

5.1. Pharmacodynamic properties

Pharmacotherapeutic group: Antipsychotics, butyrophenone derivatives
ATC code: N05AD07

Benperidol is a potent neuroleptic of the butyrophenone series with general properties similar to those of haloperidol.

5.2. Pharmacokinetic properties

After administration of benperidol (2 mg tablets PO) to volunteers, the following values have been reported:

Cmax 4.1 ± 1.7 µg/l, Tmax 2.9 ± 1.8 h, AUC(0-24) 39.8 ± 9.4 µg.h/l.

After repeated administration of 3 and 12 mg benperidol to patients, plasma levels of 10 and 30 µg/l respectively have been reported.

5.3. Preclinical safety data

No relevant information additional to that contained elsewhere in the Summary of Product Characteristics.

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