ATALINE Syrup Ref.[28137] Active ingredients: Terbutaline

Posology

When used as maintenance therapy the patient should also receive optimal anti-inflammatory therapy, e.g. inhaled corticosteroids, leukotriene receptor antagonists.

Terbutaline has a duration of action of 7 to 8 hours. The minimum recommended dosage interval is therefore 7 hours.

Adults

The starting dose should be 2 × 5ml spoonfuls 3 times in 24 hours. The dose may then be increased to 3 × 5ml spoonfuls 3 times in 24 hours if necessary to achieve adequate bronchodilation.

Elderly

Dosage as for adults.

Paediatric population

The following dosage is recommended – 0.075mg (0.25ml)/kg body weight 3 times in a 24 hour period. Not more than 15 ml 3 times in 24 hours.

Method of administration

For oral use.

Symptoms:

Headache, anxiety, tremor, nausea, tonic muscle cramps, palpitations, tachycardia, arrhythmia. A fall in blood pressure sometimes occurs.

Laboratory Findings:

Hyperglycaemia, hypokalaemia and lactic acidosis sometimesoccur.

Treatment:

Mild and Moderate Cases: Reduce the dose. Then increase the dose more slowly if the bronchospasmolytic effect is insufficient.

Severe Cases: gastric lavage, administration of activated charcoal. Determination of the acid-base balance, blood sugar and electrolytes, particularly serum potassium levels. Monitoring of the heart rate and rhythm and blood pressure. Metabolic changes should be corrected.

A cardioselective β-blocker (eg, metoprolol) is recommended for the treatment of arrhythmias causing hemodynamic deterioration. The beta-blocker should be used with care because of the possibility of inducing bronchoconstriction: use with caution on patients with a history of bronchospams. If the β₂-mediated reduction in peripheral vascular resistance significantly contributes to the fall in blood pressure, a volume expander should be given.

60 months.

Store below 25ºC.

Brown glass bottles containing 100ml of syrup.

None.