AVROTRIM Oral suspension Ref.[115629] Active ingredients: Sulfamethoxazole Trimethoprim

Source: Registered Drug Product Database (NG)  Publisher: Avro Pharma Limited, Daid House Plot 2, Block J, Limca Way, Isolo Industrial Estate, Oshodi-Apapa Expressway, Isolo, Lagos State, Nigeria, Tel: +234(1)2913955, Email: avro@rumon-org.com

Product name and form

Avrotrim Paediatric Suspension.

Pharmaceutical Form

Oral suspension.

A yellow coloured, banana flavoured suspension.

Qualitative and quantitative composition

Each 5 ml contains 40 mg Trimethoprim and 200 mg Sulfamethoxazole.

For a full list of excipients, see section 6.1.

Active Ingredient

Sulfamethoxazole competitively inhibits the utilisation of para-aminobenzoic acid in the synthesis of dihydrofolate by the bacterial cell resulting in bacteriostasis.

Trimethoprim is a dihydrofolate reductase inhibitor, inhibiting the conversion of bacterial dihydrofolic acid to tetrahydrofolic acid, required for the synthesis of some amino acids. Its effects are considerably greater on the cells of micro-organisms than on the mammalian cells.

List of Excipients

Methyl hydroxybenzoate
Sucrose
Sodium carboxymethyl cellulose
Avicel RC 581
Glycerol
Polysorbate 80
Ammonium glycyrrhizinate
Oil of aniseed
FD& C yellow No.5
Banana flavor
Ethanol 96%
Deionised water

Pack sizes and marketing

Amber glass bottles, with aluminium Ropp Screw cap and a calibrated measuring cup.

Pack size: 50 ml.

Marketing authorization holder

Avro Pharma Limited, Daid House Plot 2, Block J, Limca Way, Isolo Industrial Estate, Oshodi-Apapa Expressway, Isolo, Lagos State, Nigeria, Tel: +234(1)2913955, Email: avro@rumon-org.com

Drugs

Drug Countries
AVROTRIM Nigeria

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