BROLENE Eye ointment Ref.[27605] Active ingredients: Dibrompropamidine

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2018  Publisher: Sanofi-Aventis Ireland Ltd. T/A SANOFI, Citywest Business Campus, Dublin 24, Ireland

5.1. Pharmacodynamic properties

Dibrompropamidine is a member of the aromatic diamidine group of compounds, which possess bacteriostatic properties against a wide range of fungi and bacteria. These diamidines exert antibacterial action against pyrogenic cocci, antibiotic resistant staphylococci and some gram-negative bacilli. The activity of the diamidines is retained in the presence of organic matter such as pus and blood.

5.2. Pharmacokinetic properties

None stated.

5.3. Preclinical safety data

There is no other information available which could be of relevance to the prescriber in recognising the safety profile of Brolene and which is not included in the relevant sections of this SPC.

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